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Addendum: Accurate structure prediction of biomolecular interactions with AlphaFold 3 | Nature

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Download PDF Addendum Open access Published: 27 November 2024 Addendum: Accurate structure prediction of biomolecular interactions with AlphaFold 3 Josh Abramson, Jonas Adler, Jack Dunger, Richard Evans, Tim Green, Alexander Pritzel, Olaf Ronneberger, Lindsay Willmore, Andrew J. Ballard, Joshua Bambrick, Sebastian W. Bodenstein, David A. Evans, Chia-Chun Hung, Michael O’Neill, David Reiman, Kathryn Tunyasuvunakool, Zachary Wu, Akvilė Žemgulytė, Eirini Arvaniti, Charles Beattie, Ottavia Bertolli, Alex Bridgland, Alexey Cherepanov, Miles Congreve, …John M. Jumper Show authors

Nature volume  636,  page E4 (2024) Cite this article

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The Original Article was published on 08 May 2024

Addendum to: Nature https://doi.org/10.1038/s41586-024-07487-w Published online 8 May 2024

In our original article, we provided an extensive description in the Supplementary Information of pseudocode underlying the functioning of our AlphaFold3 model, which allows prediction of the structure of complexes including proteins, nucleic acids, small molecules, ions and modified residues. Accompanying release of the paper we provided free non-commercial access to the AlphaFold3 server (https://alphafoldserver.com/welcome). Google DeepMind has now released the underlying inference code, which can be accessed here: https://github.com/google-deepmind/alphafold3.

Author information Author notes

These authors contributed equally: Josh Abramson, Jonas Adler, Jack Dunger, Richard Evans, Tim Green, Alexander Pritzel, Olaf Ronneberger, Lindsay Willmore

These authors jointly supervised this work: Victor Bapst, Pushmeet Kohli, Max Jaderberg, Demis Hassabis, John M. Jumper

Authors and Affiliations

Core Contributor, Google DeepMind, London, UK

Josh Abramson, Jonas Adler, Jack Dunger, Richard Evans, Tim Green, Alexander Pritzel, Olaf Ronneberger, Lindsay Willmore, Andrew J. Ballard, Sebastian W. Bodenstein, David A. Evans, Michael O’Neill, David Reiman, Kathryn Tunyasuvunakool, Zachary Wu, Akvilė Žemgulytė, Victor Bapst, Pushmeet Kohli, Demis Hassabis & John M. Jumper

Core Contributor, Isomorphic Labs, London, UK

Joshua Bambrick, Chia-Chun Hung, Max Jaderberg & Demis Hassabis

Google DeepMind, London, UK

Eirini Arvaniti, Charles Beattie, Ottavia Bertolli, Alex Bridgland, Alexander I. Cowen-Rivers, Andrew Cowie, Michael Figurnov, Fabian B. Fuchs, Hannah Gladman, Rishub Jain, Yousuf A. Khan, Kuba Perlin, Anna Potapenko, Sukhdeep Singh, Ashok Thillaisundaram, Ellen D. Zhong, Michal Zielinski & Augustin Žídek

Isomorphic Labs, London, UK

Alexey Cherepanov, Miles Congreve, Caroline M. R. Low, Pascal Savy, Adrian Stecula, Catherine Tong & Sergei Yakneen

Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA

Yousuf A. Khan

Department of Computer Science, Princeton University, Princeton, NJ, USA

Ellen D. Zhong

Corresponding authors

Correspondence to Max Jaderberg, Demis Hassabis or John M. Jumper.

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Abramson, J., Adler, J., Dunger, J. et al. Addendum: Accurate structure prediction of biomolecular interactions with AlphaFold 3. Nature 636, E4 (2024). https://doi.org/10.1038/s41586-024-08416-7

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Published 27 November 2024

Version of record 27 November 2024

Issue date 12 December 2024

DOI https://doi.org/10.1038/s41586-024-08416-7

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